Latest advances in connective tissue disorders

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Latest advances in connective tissue disorders.

The connective tissue disorders comprise a number of related conditions that include systemic lupus erythematosus (SLE) and the antiphospholipid (Hughes) syndrome, scleroderma, myositis and Sjögren's syndrome. They are characterized by autoantibody production and other immune-mediated dysfunction. There are common clinical and serological features with some patients having multiple overlapping ...

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Anaesthesia in connective tissue disorders.

Patients with the more common connective tissue disorders require surgical operations more frequently than has been realized. They may present the anaesthetist with many potential problems. A few minutes of careful questioning and examination pre-operatively may prevent a tragic situation. A history of drug therapy is essential pre-operative information, particularly since many of these patient...

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Epidemiology of connective tissue disorders.

The reported prevalence and incidence of connective tissue disorders are quite variable, depending on differences in study methodology. Most important differences are the study duration, the classification criteria used for diagnosis and the country in which the study was undertaken. Sjögren's syndrome has the highest prevalence ranging between 0.5 and 3% of a given population. The prevalence o...

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Autoimmune and connective tissue disorders

Pregnant women with autoimmune rheumatic diseases, especially systemic lupus erythematosus (SLE) and systemic sclerosis, are at high risk of maternal disease flares, adverse fetal outcomes and potential drug teratogenic effects, making the management of these women particularly challenging. With improvements in diagnosis and treatment, however, these risks can be minimized by appropriate timing...

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The respiratory system in connective tissue disorders.

The connective tissue disorders (also called collagen vascular diseases) represent an heterogeneous group of immunologically mediated inflammatory disorders with a large variety of affected organs besides the lungs. The respiratory system may be involved in all its components: airways, vessels, parenchyma, pleura, respiratory muscles, etc. The frequency, clinical presentation, prognosis and res...

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ژورنال

عنوان ژورنال: Therapeutic Advances in Musculoskeletal Disease

سال: 2013

ISSN: 1759-720X,1759-7218

DOI: 10.1177/1759720x13480280